Open safety recalls, the components owners report failing most often, crash-test results and running costs for the 2025 Mercedes-Benz E 350 — assembled from NHTSA and EPA records.
Everything on this page applies to the model as a whole. Run its 17-character VIN to decode that exact car — its engine, trim, assembly plant and factory equipment — alongside these records. Free, no account.
Run a VIN →Recalls and complaints are filed against a specific model year, so figures differ from one year to the next even within a single generation. See every Mercedes-Benz E 350 year.
No EPA fuel-economy match for this model (naming may differ or it predates EPA records).
NHTSA has issued a "do not drive" warning covering 1 recall on this make, model and year. Repairs are free at any franchised dealer.
Recalls are issued per model. Confirm whether this specific car has already been repaired using its VIN — free, at any franchised dealer or on nhtsa.gov/recalls.
NHTSA lists 2 recalls for this make/model/year. Recalls apply to the model, so some may already be fixed on this specific car — check with a dealer using the VIN.
Issue: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2025 E 350, E 350 4MATIC, E 450 4MATIC, and E450 4MATIC station wagon vehicles. The camber strut bracket may have been improperly welded onto the rear axle carrier, possibly resulting in separation of the bracket from the rear axle carrier.
Risk: Rear axle carrier failure can cause a sudden loss of vehicle handling and control, increasing the risk of a crash.
Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will replace the rear axle carrier, free of charge. Owner notification letters were mailed January 22, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024120015.
Campaign 24V941000
Issue: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2024-2026 AMG GT, C-Class, E-Class, SL, CLE, and GLC vehicles. The infotainment control unit may reset while the vehicle is in motion and cause the instrument panel display to go blank.
Risk: An instrument panel display that fails to show critical safety information, such as the speedometer and warning lights, increases the risk of a crash.
Remedy: Dealers will update the infotainment control unit software, free of charge. Owner notification letters were mailed June 29, 2026. MBUSA's number for this recall is 2026050004. Owners may contact MBUSA customer service at 1-800-367-6372. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning May 8, 2026.
Campaign 26V281000
The parts named most often across 2 owner complaintsfiled with NHTSA for this make, model and year — the closest free answer to “what is likely to go wrong?”
Complaints are self-reported and skew toward problems people find alarming, so treat this as where to look, not a defect rate.
The digital instrument cluster and center infotainment display screen went completely black and blank while the vehicle was in motion. This immediate failure blinded the driver to critical safety telemetry, including the current vehicle speed, gear positioning, and active safety warning telltales, creating an immediate, severe crash hazard on the roadway.This symptom is identical to the failure condition detailed in active NHTSA Safety Recall Campaign 26V281000 for this exact model year. The vehicle is currently held at an authorized Mercedes-Benz dealership (Mercedes-Benz of West Covina) where technicians confirmed the physical screen and plug blackout but are actively refusing to execute the safety recall remedy without a $1,272.95 out-of-pocket consumer diagnostic fee, falsely claiming a localized cosmetic stain on a connection plug voids the manufacturer's obligation to repair a known, federally acknowledged factory software design defect.The vehicle remains unmodified, intact, and available for federal or corporate engineering inspection at the dealership location upon request. No warning lamps or symptoms appeared prior to the sudden screen blackout.
Drove the car through a 6" puddle and the engine was hydro locked, alternator and starter died leaving me stranded in the middle of the road. This car is in Florida and I would expect it to be able to go through a puddle. When getting the engine replaced I was told that my E350 was not the only one with this issue.
NHTSA has no NCAP crash-test rating for this model/year (common for older, low-volume, or heavy-duty vehicles).